Isobuscaline

Isobuscaline
Clinical data
Other names4-Isobutoxy-3,5-dimethoxyphenethylamine; 3,5-Dimethoxy-4-isobutoxyphenethylamine
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action8–14 hours[1]
Identifiers
  • 2-[3,5-dimethoxy-4-(2-methylpropoxy)phenyl]ethanamine
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC14H23NO3
Molar mass253.342 g·mol−1
3D model (JSmol)
  • CC(C)COC1=C(C=C(C=C1OC)CCN)OC
  • InChI=1S/C14H23NO3/c1-10(2)9-18-14-12(16-3)7-11(5-6-15)8-13(14)17-4/h7-8,10H,5-6,9,15H2,1-4H3
  • Key:KNAFUDQAABKKDG-UHFFFAOYSA-N

Isobuscaline (IB), also known as 4-isobutoxy-3,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and scaline families related to mescaline.[1][2] It is the analogue and skeletal isomer of buscaline in which there is an isobutoxy group instead of a butoxy group at the 4 position.[1][2] The drug's dose range is 60 to 100 mg orally and its duration is 8 to 14 hours.[1] Its effects included little in the way of psychedelic visuals, no enhanced fantasy, and body load.[1] The chemical synthesis of isobuscaline has been described.[2] The drug was described in the scientific literature by Daniel Trachsel in 2002.[2] It is not a controlled substance in Canada as of 2025.[3]

See also

References

  1. ^ a b c d e f Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. pp. 705, 715, 717, 736. ISBN 978-3-03788-700-4. OCLC 858805226.
  2. ^ a b c d Trachsel D (2002). "Synthese von neuen (Phenylalkyl)aminen zur Untersuchung von Struktur-Aktivitätsbeziehungen, Mitteilung 1, Mescalin Derivate". Helvetica Chimica Acta. 85 (9): 3019–3026. doi:10.1002/1522-2675(200209)85:9<3019::AID-HLCA3019>3.0.CO;2-4.
  3. ^ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
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