6-EAPB
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| Other names | 1-(Benzofuran-6-yl)-N-ethylpropan-2-amine |
| Legal status | |
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| Chemical and physical data | |
| Formula | C13H17NO |
| Molar mass | 203.285 g·mol−1 |
| 3D model (JSmol) | |
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6-EAPB, also known as 1-(benzofuran-6-yl)-N-ethylpropan-2-amine, is a potentially psychedelic and potentially entactogenic drug of the benzofuran class;[1] it is structurally related to 6-APB and MDMA.
Pharmacology
Pharmacodynamics
6-EAPB is a potent monoamine reuptake inhibitor.[2] It shows very low potency as a serotonin 5-HT2A receptor agonist.[2]
Society and culture
Legal status
As an N-ethyl derivative of 6-APB, 6-EAPB fell outside the scope of the Temporary Class Drug ban issued by the Home Office on June 10, 2013.[3] The ACMD has advised that 6-EAPB (and other benzofurans) are moved to Class B,[4] this came into action on 10 June 2014.[5]
See also
References
- ^ Taschwer M, Hofer MG, Schmid MG (October 2014). "Enantioseparation of benzofurys and other novel psychoactive compounds by CE and sulfobutylether β-cyclodextrin as chiral selector added to the BGE". Electrophoresis. 35 (19): 2793–2799. doi:10.1002/elps.201400164. PMID 24930967. S2CID 2937770.
- ^ a b Stalberga, D., Kronstrand, R., Schranz, B., van Zijl, N., Karlman, S., Aref, S., ... & Gréen, H. (2025). Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor. https://doi.org/10.22541/au.176253891.19158813/v1
- ^ "Temporary class drug order on benzofury and NBOMe compounds". Retrieved 15 June 2015.
- ^ "ACMD recommends permanent ban on two "legal highs"". Retrieved 15 June 2015.
- ^ "Ban on NBOMe and benzofurans comes into force". Retrieved 15 June 2015.