2C-T-28

2C-T-28
Clinical data
Other names4-(3-Fluoropropylthio)-2,5-dimethoxyphenethylamine; 2C-T-FP
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action8–10 hours[1]
Identifiers
  • 2-[4-(3-fluoropropylsulfanyl)-2,5-dimethoxyphenyl]ethanamine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H20FNO2S
Molar mass273.37 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C=C1CCN)OC)SCCCF
  • InChI=1S/C13H20FNO2S/c1-16-11-9-13(18-7-3-5-14)12(17-2)8-10(11)4-6-15/h8-9H,3-7,15H2,1-2H3
  • Key:XAFVGDRNPGLCMI-UHFFFAOYSA-N

2C-T-28, also known as 4-(3-fluoropropylthio)-2,5-dimethoxyphenethylamine, is a psychedelic drug related to 2C-T-7 and 2C-T-21. It was named by Alexander Shulgin but was never made or tested by him, and was instead first synthesised by Daniel Trachsel some years later. It has a binding affinity of 75 nM at 5-HT2A and 28 nM at 5-HT2C. It is reportedly a potent psychedelic drug with an active dose in the 8–20 mg range, and a duration of action of 8–10 hours, with prominent visual effects. 2C-T-28 is the 3-fluoropropyl instead of 2-fluoroethyl chain-lengthened homologue of 2C-T-21 and has very similar properties, although unlike 2C-T-21 it will not form toxic fluoroacetate as a metabolite.[2][1] It is a controlled substance in Canada under phenethylamine blanket-ban language.[3]

See also

References

  1. ^ a b c Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. pp. 789–794. ISBN 978-3-03788-700-4.
  2. ^ Shulgin A, Manning T, Daley PF (2011). The Shulgin Index. Volume 1. Psychedelic Phenethylamines and Related Compounds. Transform Press. p. 346. ISBN 978-0-9630096-3-0.
  3. ^ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
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