Mescaloxylic acid

Mescaloxylic acid
Clinical data
Other names	N-Carboxymethylmescaline; N-Carboxymethyl-3,4,5-trimethoxyphenethylamine; N-[2-(3,4,5-Trimethoxyphenyl)ethyl]glycine
ATC code	None;
Identifiers
	IUPAC name 2-[2-(3,4,5-trimethoxyphenyl)ethylamino]acetic acid;
CAS Number	7738-40-1;
PubChem CID	57478618;
ChemSpider	74204288;
Chemical and physical data
Formula	C13H19NO5
Molar mass	269.297 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=CC(=CC(=C1OC)OC)CCNCC(=O)O;
	InChI InChI=1S/C13H19NO5/c1-17-10-6-9(4-5-14-8-12(15)16)7-11(18-2)13(10)19-3/h6-7,14H,4-5,8H2,1-3H3,(H,15,16); Key:OUKOSEIHBSLNGJ-UHFFFAOYSA-N;

Mescaloxylic acid, also known as N-carboxymethylmescaline or as N-carboxymethyl-3,4,5-trimethoxyphenethylamine, is an alkaloid of the phenethylamine and scaline families related to the psychedelic drug mescaline.^[1]^[2]^[3]^[4]^[5] It is the N-carboxy methyl derivative of mescaline.^[1]^[2]^[3] The alkaloid has been reported to be a trace constituent of peyote (Lophophora williamsii), though findings appear conflicting.^[1]^[2]^[3]^[4]^[5] It was first described in the scientific literature by 1972.^[1]^[3]

References

^ ^a ^b ^c ^d "TroutsNotes". isomerdesign.com.
^ ^a ^b ^c Saxton JE, Shamma M (1 January 1973). "The isoquinoline alkaloids". The Alkaloids. The Royal Society of Chemistry. pp. 116–168. doi:10.1039/9781847555892-00116. ISBN 978-0-85186-277-4.
^ ^a ^b ^c ^d Kapadia GJ, Hussain MH, Rao GS (July 1972). "Peyote and related alkaloids. XIV. Mescaloxylic acid and mescaloruvic acid, the novel amino acid analogs of mescaline". Journal of Pharmaceutical Sciences. 61 (7): 1172–1173. Bibcode:1972JPhmS..61.1172K. doi:10.1002/jps.2600610733. PMID 5044824.
^ ^a ^b Wagner I, Musso H (1983). "New Naturally Occurring Amino Acids". Angewandte Chemie International Edition in English. 22 (11): 816–828. doi:10.1002/anie.198308161. ISSN 0570-0833.
^ ^a ^b Olive MF, Triggle DJ (2007). Peyote and Mescaline. Infobase Publishing. ISBN 978-1-4381-0214-6. Retrieved 10 June 2026.