5,6-MeO-MiPT

5,6-MeO-MiPT
Clinical data
Other names5,6-Dimethoxy-N-methyl-N-isopropyltryptamine
Routes of
administration		Oral[1]
Drug classSerotonin receptor modulator
ATC code
  • None
Pharmacokinetic data
Onset of actionUnknown[1]
Duration of actionUnknown[1]
Identifiers
  • N-[2-(5,6-dimethoxy-1H-indol-3-yl)ethyl]-N-methylpropan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H24N2O2
Molar mass276.380 g·mol−1
3D model (JSmol)
  • CC(C)N(C)CCc2c[nH]c1cc(OC)c(OC)cc12
  • InChI=1S/C16H24N2O2/c1-11(2)18(3)7-6-12-10-17-14-9-16(20-5)15(19-4)8-13(12)14/h8-11,17H,6-7H2,1-5H3
  • Key:XXWWFLAMFUOAQG-UHFFFAOYSA-N

5,6-MeO-MiPT, also known as 5,6-dimethoxy-N-methyl-N-isopropyltryptamine, is a chemical compound of the tryptamine family.[1] It is the 5,6-dimethoxy derivative of methylisopropyltryptamine (MiPT) and is an analogue of 5-MeO-MiPT.[1] In his 1991 book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin listed the dose as greater than 75 mg orally and the duration as unknown.[1] The drug produced few to no effects at doses of up to 75 mg orally.[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of 5,6-MeO-MiPT.[1] However, the drug has been found to have abolished or profoundly reduced affinities for serotonin receptors compared to psychedelic tryptamines like MiPT and 5-MeO-MiPT.[2] Its chemical synthesis has been described.[1] 5,6-MeO-MiPT was first described in the scientific literature by David Repke and Alexander Shulgin and colleagues.[3]

See also

References

  1. ^ a b c d e f g h i Shulgin, Alexander; Shulgin, Ann (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
  2. ^ McKenna DJ, Repke DB, Lo L, Peroutka SJ (March 1990). "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology. 29 (3): 193–198. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.
  3. ^ Repke DB, Grotjahn DB, Shulgin AT (July 1985). "Psychotomimetic N-methyl-N-isopropyltryptamines. Effects of variation of aromatic oxygen substituents". J Med Chem. 28 (7): 892–896. doi:10.1021/jm00145a007. PMID 4009612.
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