+ 2 reduced
ferredoxin
Phycoerythrobilin synthase
| Phycoerythrobilin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.7.6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Phycoerythrobilin synthase (EC 1.3.7.6, PebS) is an enzyme with systematic name (3Z)-phycoerythrobilin:ferredoxin oxidoreductase (from biliverdin IX alpha).[1][2] It catalyses the following chemical reaction
This enzyme, from a cyanophage infecting oceanic cyanobacteria of the Prochlorococcus genus carries out in one step the reduction of biliverdin to (3Z)-phycoerythrobilin. The same overall reaction results from the action of 15,16-dihydrobiliverdin:ferredoxin oxidoreductase and phycoerythrobilin:ferredoxin oxidoreductase in oxygenic organisms.[3][4]
References
- ^ Dammeyer T, Bagby SC, Sullivan MB, Chisholm SW, Frankenberg-Dinkel N (March 2008). "Efficient phage-mediated pigment biosynthesis in oceanic cyanobacteria". Current Biology. 18 (6): 442–8. Bibcode:2008CBio...18..442D. doi:10.1016/j.cub.2008.02.067. PMID 18356052.
- ^ Dammeyer, Thorben; Hofmann, Eckhard; Frankenberg-Dinkel, Nicole (2008). "Phycoerythrobilin Synthase (PebS) of a Marine Virus". Journal of Biological Chemistry. 283 (41): 27547–27554. doi:10.1074/jbc.M803765200. PMID 18662988.
- ^ Enzyme 1.3.7.6 at KEGG Pathway Database.
- ^ Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC (2001). "Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms". Plant Cell. 13 (4): 965–78. Bibcode:2001PlanC..13..965F. doi:10.1105/tpc.13.4.965. PMC 135530. PMID 11283349.
External links
- Phycoerythrobilin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)