Phloroglucinol reductase
| phloroglucinol reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.57 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, phloroglucinol reductase (EC 1.3.1.57) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are dihydrophloroglucinol (1) and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are phloroglucinol (2), reduced NADPH, and a proton.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dihydrophloroglucinol:NADP+ oxidoreductase. This enzyme participates in benzoate degradation via CoA ligation.
References
- ^ Enzyme 1.3.1.57 at KEGG Pathway Database.
- ^ Haddock JD, Ferry JG (1989). "Purification and properties of phloroglucinol reductase from Eubacterium oxidoreducens G-41". J. Biol. Chem. 264 (8): 4423–7. doi:10.1016/S0021-9258(18)83759-0. PMID 2925649.