Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase

cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
Identifiers
EC no.1.3.1.49
CAS no.118390-61-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase (EC 1.3.1.49) is an enzyme that catalyzes the chemical reaction

3,4-dihydrophenanthrene-3,4-diol
 
 
 
H+
 
H+
 
phenanthrene-3,4-diol
 

The two substrates of this enzyme are (3S,4R)-3,4-dihydrophenanthrene-3,4-diol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are phenanthrene-3,4-diol, reduced NADH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.

References

  1. ^ Enzyme 1.3.1.49 at KEGG Pathway Database.
  2. ^ Nagao K, Takizawa N, Kiyahara H (1988). "Purification and properties of cis-phenanthrene dihydrodiol dehydrogenase in Alcaligenes faecalis AFK2". Agric. Biol. Chem. 52 (10): 2621–2623. doi:10.1271/bbb1961.52.2621.