Anterior ethmoidal nerve
| Anterior ethmoidal nerve | |
|---|---|
The ophthalmic artery and its branches. (Nerve not pictured, but location is similar to artery.) | |
| Details | |
| From | Nasociliary nerve |
| Innervates | Meninges, nasal cavity, skin of nose |
| Identifiers | |
| Latin | nervus ethmoidalis anterior |
| TA98 | A14.2.01.030 |
| TA2 | 6208 |
| FMA | 52675 |
| Anatomical terms of neuroanatomy | |
The anterior ethmoidal nerve is a nerve of the head.[1] It is a sensory branch of the nasociliary nerve (itself a branch of the ophthalmic nerve (CN V1)).[2] It arises in the orbit, and enters first the cranial cavity and then the nasal cavity.[3] It provides sensory innervation to part of the meninges, nasal cavity, and part of the skin of the nose.[4] The nerve is relevant in conditions involving nasal sensation and in surgical procedures of the skull base and nasal cavity.[5]
Structure
Origin
The anterior ethmoidal nerve is a terminal branch of the nasociliary nerve, a branch of the ophthalmic nerve (CN V1), itself a branch of the trigeminal nerve (CN V).[6] It branches near the medial wall of the orbit.
Course
It passes through the anterior ethmoidal canal alongside the anterior ethmoidal artery[1]: 780 and vein[1]: 566 to emerge in anterior cranial fossa through the anterior ethmoidal foramen[1]: 1464.e13 (at the junction of the cribiform plate of ethmoid bone and orbital part of frontal bone[1]: 566 ).
Within the cranial cavity, it passes anterior-ward (external to the dura mater) along a groove upon the superior surface of the cribriform plate. It descends through an aperture situated lateral to the crista galli to reach the nasal cavity.[1]: 1464.e13
In the nasal cavity, it passes along a groove upon the internal aspect of the nasal bone, and issuing the medial and lateral internal nasal branches.[1]: 1464.e13
It is continued as the external nasal nerve beyond the inferior margin of the nasal bone.[1]: 1464.e13
Distribution
Within the anterior cranial fossa, it gives sensory fibers to the meninges to provide sensory innervation to part of the meninges.[7]
Its medial internal nasal branch innervates the superior and anterior portions of the nasal septum.[1]: 1464.e13
Its lateral internal nasal branch innervates the anterior portion of the lateral nasal wall.[1]: 1464.e13
It gives off branches to the roof of the nasal cavity, and bifurcates into a lateral internal nasal branch and medial internal nasal branch. It sends sensory fibers to the anterior ethmoid air cells and the middle ethmoidal air cells.[4]
Its terminal branch - the external nasal nerve - innervates skin of the nose between the nasal bones superiorly and the tip of the nose inferiorly, except the alar portion surrounding the external nares.[1]: 1464.e13
Function
It is involved in the diving reflex.[8]
Disease
Chronic pain in this region is known as Anterior Ethmoidal Nerve Syndrome, or AENS.[9] One cause of this is compression of the surrounding nerve which causes sphenopalatine ganglion neuralgia, with similar clinical findings of a cluster headache, outside of further nasal symptoms.[10] Potential treatments include the injection of anesthetics or, in more serious cases, a partial turbinectomy. The syndrome was featured in season 3, episode 5 of Grey's Anatomy.
References
- ^ a b c d e f g h i j k Standring, Susan (2020). Gray's Anatomy: The Anatomical Basis of Clinical Practice (42th ed.). New York. ISBN 978-0-7020-7707-4. OCLC 1201341621.
{{cite book}}: CS1 maint: location missing publisher (link) - ^ Monkhouse, Stanley (2006). Cranial nerves: functional anatomy. Cambridge, UK: Cambridge University Press. ISBN 978-0-521-61537-2.
- ^ Rhoton, Albert L. (2002-10-01). "The Anterior and Middle Cranial Base". Neurosurgery. 51 (suppl_4): S1–273-S1-302. doi:10.1097/00006123-200210001-00007. ISSN 0148-396X.
- ^ a b Sobiesk, John L.; Munakomi, Sunil (2026), "Anatomy, Head and Neck, Nasal Cavity", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31334952, retrieved 2026-03-10
- ^ Moon, Hyoung‐Jin; Kim, Hyun‐Ung; Lee, Jeung‐Gweon; Chung, In Hyuk; Yoon, Joo‐Heon (May 2001). "Surgical Anatomy of the Anterior Ethmoidal Canal in Ethmoid Roof". The Laryngoscope. 111 (5): 900–904. doi:10.1097/00005537-200105000-00027. ISSN 0023-852X.
- ^ Lucier, Gregory E.; Egizii, Rita (1986). "Central projections of the ethmoidal nerve of the cat as determined by the horseradish peroxidase tracer technique". Journal of Comparative Neurology. 247 (1): 123–132. doi:10.1002/cne.902470108. ISSN 1096-9861. PMID 3711374. S2CID 23040741.
- ^ Shimizu, Toshihiko; Suzuki, Norihiro (2010). "3 - Biological sciences related to headache". Handbook of Clinical Neurology. Vol. 97. Elsevier. pp. 35–45. doi:10.1016/S0072-9752(10)97003-6. ISBN 978-0-444-52139-2. ISSN 0072-9752. PMID 20816409.
- ^ Rybka, E. J.; McCulloch, P. F. (23 February 2006). "The anterior ethmoidal nerve is necessary for the initiation of the nasopharyngeal response in the rat". Brain Research. 1075 (1): 122–132. doi:10.1016/j.brainres.2005.12.112. ISSN 0006-8993. PMID 16466647. S2CID 37900942.
- ^ Burnham, Howard H. (1 November 1949). "THE ANTERIOR ETHMOIDAL NERVE SYNDROME<subtitle>Referred Pain and Headache from the Lateral Nasal Wall</subtitle>". Archives of Otolaryngology. p. 640. doi:10.1001/archotol.1949.00700010654011.
- ^ He, Wei; Zhang, Yixin; Long, Ting; Pan, Qi; Zhang, Shanshan; Zhou, Jiying (2019). "Sphenopalatine Neuralgia: An Independent Neuralgia Entity. Pooled Analysis of a Case Series and Literature Review". Headache: The Journal of Head and Face Pain. pp. 358–370. doi:10.1111/head.13469. Retrieved 4 January 2026.