Timothy Ryan (biochemist)
Timothy A. Ryan | |
|---|---|
| Alma mater | McGill University (BSc, MSc) Cornell University (PhD) |
| Known for | Presynaptic biology Local ATP synthesis at synapses Optical reporters of synaptic function |
| Awards | National Academy of Sciences (2024) American Academy of Arts and Sciences (2024) Javits Award (2016) McKnight Technological Innovations in Neuroscience Award (2000, 2010) |
| Scientific career | |
| Fields | Neuroscience, Biophysics |
| Institutions | Weill Cornell Medicine Howard Hughes Medical Institute |
| Doctoral advisor | Watt W. Webb |
| Website | sites |
Timothy A. Ryan is an American neuroscientist and biophysicist. He is a Tri-Institutional Professor of Biochemistry at Weill Cornell Medicine and a Senior Scholar at the Howard Hughes Medical Institute (HHMI) Janelia Research Campus.[1] He is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences.[2]
Education
Ryan received his Bachelor of Science and Master of Science in Physics from McGill University.[2] He earned his Ph.D. in Physics from Cornell University.[2] He conducted postdoctoral research in molecular and cellular physiology in the laboratory of Stephen J Smith at Stanford University before joining the faculty at Weill Cornell Medicine in 1997.[2]
Research
Ryan's research focuses on the molecular mechanisms of synaptic function, with a particular emphasis on presynaptic biology and neuroenergetics.[2] His laboratory developed quantitative optical techniques to measure parameters associated with synaptic transmission.[2] His work discovered that nerve terminals are highly sensitive to metabolic perturbations and that synapses must regulate ATP synthesis on-demand to match the bioenergetic needs of neurotransmitter release and recycling.[2] He has also identified links between susceptibility genes for Parkinson's disease and the failure of synapses to maintain bioenergetic balance.[2] In 2024, his team was awarded a significant grant from the Michael J. Fox Foundation to study organelle integration in Parkinson's disease.[3]
Awards and honors
- 2024: Elected member of the National Academy of Sciences[4]
- 2024: Elected member of the American Academy of Arts and Sciences[5]
- 2016: NINDS Javits Neuroscience Investigator Award[6]
- 2000, 2010: McKnight Endowment Fund for Neuroscience Technological Innovations in Neuroscience Award[7]
- 1999: Sloan Research Fellowship[8]
References
- ^ "Team: Timothy Ryan". Aligning Science Across Parkinson's (ASAP). Retrieved 3 January 2026.
- ^ a b c d e f g h "Member Directory: Timothy A. Ryan". National Academy of Sciences. Retrieved 3 January 2026.
- ^ "Timothy Ryan, PhD". Michael J. Fox Foundation. 21 November 2024. Retrieved 3 January 2026.
- ^ "National Academy of Sciences Elects Members and International Members". National Academy of Sciences. 30 April 2024. Retrieved 3 January 2026.
- ^ "Timothy A. Ryan". American Academy of Arts and Sciences. Retrieved 3 January 2026.
- ^ "Javits Neuroscience Investigator Award (R37) Recipients". National Institute of Neurological Disorders and Stroke. Retrieved 3 January 2026.
- ^ "Awardees: Technological Innovations in Neuroscience". McKnight Foundation. Retrieved 3 January 2026.
- ^ "Sloan Research Fellowships 1999 Annual Report" (PDF). Alfred P. Sloan Foundation. Retrieved 3 January 2026.