Tartrate dehydrogenase
| tartrate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Tartrate dehydrogenase tetramer, Pseudomonas putida | |||||||||
| Identifiers | |||||||||
| EC no. | 1.1.1.93 | ||||||||
| CAS no. | 37250-29-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, tartrate dehydrogenase (EC 1.1.1.93) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are meso-tartaric acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 2-hydroxy-3-oxosuccinic acid, reduced NADH, and a proton. The enzyme can also act on the stereoisomer (+)-tartaric acid, giving the same product.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is tartrate:NAD+ oxidoreductase. This enzyme is also called mesotartrate dehydrogenase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, manganese.
References
- ^ Enzyme 1.1.1.93 at KEGG Pathway Database.
- ^ Kohn LD, Packman PM, Allen RH, Jakoby WB (1968). "Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase". J. Biol. Chem. 243 (10): 2479–85. doi:10.1016/S0021-9258(18)93400-9. PMID 4297261.