Stomoxyn

Stomoxyn
Identifiers
SymbolStomoxyn
PfamPF11585
InterProIPR021037
OPM superfamily151
OPM protein1zrv
Available protein structures:
PDB  IPR021037 PF11585 (ECOD; PDBsum)  
AlphaFold

Stomoxyn is an insect antimicrobial peptide localised in the gut epithelium, which functions in killing a range of microorganisms, parasites and some viruses. In water, stomoxyn has a flexible random coil in structure, while in trifluoroethanol it adopts a stable helical structure. Structural similarities to the antimicrobial peptide cecropin A from Hyalophora cecropia suggest that it may function in a similar manner by disrupting the bacterial membrane.[1]

References

  1. ^ Landon C, Meudal H, Boulanger N, Bulet P, Vovelle F (February 2006). "Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation". Biopolymers. 81 (2): 92–103. doi:10.1002/bip.20370. PMID 16170803. S2CID 24098919.
This article incorporates text from the public domain Pfam and InterPro: IPR021037


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