Quinaldic acid

Quinaldic acid
Names
	IUPAC name quinoline-2-carboxylic acid
	Other names 2-Carboxyquinoline; 2-Quinolinecarboxylic acid
Identifiers
CAS Number	93-10-7;
3D model (JSmol)	Interactive image;
Beilstein Reference	126322
ChEBI	CHEBI:18386;
ChEMBL	ChEMBL1160559;
DrugBank	DB02428;
ECHA InfoCard	100.002.018
EC Number	202-218-3;
Gmelin Reference	143145
KEGG	C06325;
PubChem CID	7124;
UNII	P90NWT719R;
CompTox Dashboard (EPA)	DTXSID6059079 ;
	InChI InChI=1S/C10H7NO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H,12,13) Key: LOAUVZALPPNFOQ-UHFFFAOYSA-N;
	SMILES C1=CC=C2C(=C1)C=CC(=N2)C(=O)O;
Properties
Chemical formula	C10H7NO2
Molar mass	173.171 g·mol−1
Solubility in water	14000 mg/L
Hazards
	GHS labelling:[1]
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Quinaldic acid is an organic chemical compound.^[1]^[2]^[3]^[4]

Quinaldic acid can form a zwitterion, where a proton is transferred from the carboxylic acid group to the nitrogen atom.^[5] Neptunium and uranium can form mixed ligand compounds with quinaldic acid.^[5]

Quinaldic acid has been used in the gravimetric analysis of uranium in the form of uranyl ion. This is precipitated by forming an insoluble salt with quinaldic acid. When incinerated U₃O₈ is formed and can be weighed.^[6]

References

^ PubChem. "Quinaldic Acid". pubchem.ncbi.nlm.nih.gov. Retrieved 2025-12-09.
^ "Quinaldic Acid". go.drugbank.com. Retrieved 2025-12-09.
^ PubChem. "Quinaldic acid, 1,2,3,4-tetrahydro-8-hydroxy-4-oxo-, L-". pubchem.ncbi.nlm.nih.gov. Retrieved 2025-12-09.
^ Tajieva, Galiya R.; Ali Siddique, Sabir; Ibragimov, Aziz B.; Mohamed, Shaaban K.; Ibragimova, Mavlyuda R.; Abuelizz, Hatem A.; Al-Salahi, Rashad; M.Ashurov, Jamshid; Ibragimov, Bakhtiyar T.; Gao, Junkuo; El Bakri, Youness (2024-08-01). "Synthesis and characterization of novel quinaldic acid based Ni, Fe, and Cr Complexes: A computational and experimental study". Inorganic Chemistry Communications. 166 112590. doi:10.1016/j.inoche.2024.112590. ISSN 1387-7003.
^ ^a ^b Andreev, Grigory; Budantseva, Nina; Fedoseev, Aleksander (September 2022). "The novel U(VI) and Np(VI) mixed-ligand complexes based on quinaldic acid zwitterion". Polyhedron. 224 116003. doi:10.1016/j.poly.2022.116003.
^ Ware, Elinor (1947). Organic Reagents for Uranium Analysis. Technical Information Division, Oak Ridge Operations. p. 18.

[1] PubChem. "Quinaldic Acid". pubchem.ncbi.nlm.nih.gov. Retrieved 2025-12-09.

[2] "Quinaldic Acid". go.drugbank.com. Retrieved 2025-12-09.

[3] PubChem. "Quinaldic acid, 1,2,3,4-tetrahydro-8-hydroxy-4-oxo-, L-". pubchem.ncbi.nlm.nih.gov. Retrieved 2025-12-09.

[4] Tajieva, Galiya R.; Ali Siddique, Sabir; Ibragimov, Aziz B.; Mohamed, Shaaban K.; Ibragimova, Mavlyuda R.; Abuelizz, Hatem A.; Al-Salahi, Rashad; M.Ashurov, Jamshid; Ibragimov, Bakhtiyar T.; Gao, Junkuo; El Bakri, Youness (2024-08-01). "Synthesis and characterization of novel quinaldic acid based Ni, Fe, and Cr Complexes: A computational and experimental study". Inorganic Chemistry Communications. 166 112590. doi:10.1016/j.inoche.2024.112590. ISSN 1387-7003.

[and-5] Andreev, Grigory; Budantseva, Nina; Fedoseev, Aleksander (September 2022). "The novel U(VI) and Np(VI) mixed-ligand complexes based on quinaldic acid zwitterion". Polyhedron. 224 116003. doi:10.1016/j.poly.2022.116003.

[6] Ware, Elinor (1947). Organic Reagents for Uranium Analysis. Technical Information Division, Oak Ridge Operations. p. 18.

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