Propanediol-phosphate dehydrogenase

propanediol-phosphate dehydrogenase
Identifiers
EC no.1.1.1.7
CAS no.9028-15-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction

Propanediol 1-phosphate
+ NAD+
 
 
 
H+
 
H+
 
Hydroxyacetone phosphate
 

The two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+. Its products are hydroxyacetone phosphate, nicotinamide adenine dinucleotide (NADH), and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD+ oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD+ oxidoreductase, and propanediol phosphate dehydrogenase.

References

  1. ^ Enzyme 1.1.1.7 at KEGG Pathway Database.
  2. ^ Sellinger OZ, Miller ON (July 1959). "The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase". The Journal of Biological Chemistry. 234 (7): 1641–6. doi:10.1016/S0021-9258(18)69897-7. PMID 13672935.
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