Portal:Music/DateOfBirth/September 22
- King Sunny Adé, Nigerian musician, singer and songwriter, turns 80.
- David Coverdale, American vocalist with Deep Purple, Whitesnake, turns 75.
- Richard Fairbrass, British singer from the band Right Said Fred, turns 73.
- Tony DaGradi, American tenor saxophonist, turns 73.
- Debby Boone, American vocalist, turns 70.
- Johnette Napolitano, American bassist, songwriter, and lead vocalist for Concrete Blonde, turns 69.
- Nick Cave, Australian vocalist with Nick Cave and the Bad Seeds, turns 69.
- Andrea Bocelli, Renowned opera singer, turns 68.
- Joan Jett, American rock and roll musician, turns 68.
- Shari Belafonte, American singer and actress; daughter to Harry Belafonte, turns 68.
- Ken Vandermark, American jazz saxophonist, turns 62.
- Andy Cairns, guitarist and vocalist for Therapy?, turns 61.
- Matt Sharp, American bassist for Weezer, turns 57.
- Rah Digga, American rapper, turns 56.
- Chesney Hawkes, Brit vocalist, turns 55.
- Big Rube, American R&B singer with Society of Soul and Dungeon Family, turns 55.
- Marlena Shaw (September 22, 1942 –January 19, 2024), American jazz vocalist, would have turned 84 this year.
- Bill Smith (September 22, 1926–February 29, 2020), American composer and clarinettist, would have turned 100 this year.
- Ray Wetzel (September 22, 1924 –August 17, 1951), American jazz trumpeter, would have turned 102 this year.
- Rio De Gregori (September 22, 1919 –May 22, 1987), Swiss pianist, would have turned 107 this year.
- Fletcher Smith (September 22, 1913 –August 15, 1993), American session musician; pianist who worked with Slim Gaillard, Big Maybelle, Earl Bostic, Percy Mayfield, and Stick McGhee, would have turned 113 this year.