Palmitoyl tripeptide-38

Palmitoyl tripeptide-38
Identifiers
  • (2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-4-methylsulfonylbutanoyl]amino]hexanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC33H65N5O7S
Molar mass675.97 g·mol−1
3D model (JSmol)
  • CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)N[C@@H](CCCCN)C(=O)O
  • InChI=1S/C33H65N5O7S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-22-30(39)36-27(20-16-18-24-34)31(40)37-28(23-26-46(2,44)45)32(41)38-29(33(42)43)21-17-19-25-35/h27-29H,3-26,34-35H2,1-2H3,(H,36,39)(H,37,40)(H,38,41)(H,42,43)/t27-,28-,29-/m0/s1
  • Key:RGXYBFJDNNODFP-AWCRTANDSA-N

Palmitoyl Tripeptide-38 (Pal-Lys-Met(O2)-Lys, Matrixyl Synthe’6) is a tripeptide that is derived from a sequence found in the connective tissue proteins collagen VI and laminin, conjugated with a lipophilic palmitoyl chain for improved absorption into the skin. It is claimed to stimulate endogenous biosynthesis of collagens, fibronectin, hyaluronic acid and laminin, and is used in skincare products for its purported anti-aging effects.[1][2]

See also

References

  1. ^ Schagen S (2017). "Topical Peptide Treatments with Effective Anti-Aging Results". Cosmetics. 4 (2): 16. doi:10.3390/cosmetics4020016.
  2. ^ Lintner K, Gerstein F, Solish N (December 2020). "A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos® analysis and frequently repeated auto-perception". Journal of Cosmetic Dermatology. 19 (12): 3262–3269. doi:10.1111/jocd.13770. PMC 7756752. PMID 33103342.
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