Nicotianamine aminotransferase
| Nicotianamine aminotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.80 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Nicotianamine aminotransferase (EC 2.6.1.80) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are nicotianamine and 2-oxoglutaric acid. Its products are 3"-deamino-3"-oxonicotianamine and glutamic acid.[1][2][3]
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is nicotianamine:2-oxoglutarate aminotransferase; nicotianamine transaminase. Other names in common use include NAAT, NAAT-I, NAAT-II, and NAAT-III.
Both the starting material and product of this enzyme are phytosiderophores that help higher plants absorb metal ions from soil.[4][5]
References
- ^ Enzyme 2.6.1.80 at KEGG Pathway Database.
- ^ Mori S; Higuchi, Kyoko; Nishizawa, Naoko-Kishi; Fushiya, Shinji; Chino, Mitsuo; Mori, Satoshi (1994). "Nicotianamine aminotransferase activities are correlated with the phytosiderophore secretions under Fe-deficient conditions in Gramineae". J. Exp. Bot. 45 (12): 1903–1906. doi:10.1093/jxb/45.12.1903.
- ^ Schaaf G, Ludewig U, Erenoglu BE, Mori S, Kitahara T, von Wiren N (2004). "ZmYS1 functions as a proton-coupled symporter for phytosiderophore- and nicotianamine-chelated metals". J. Biol. Chem. 279 (10): 9091–6. doi:10.1074/jbc.M311799200. PMID 14699112.
- ^ S; Yamaguchi, H; Nakanishi, H; Shioiri, T; Nishizawa, NK; Mori, S (1999). "Cloning Two Genes for Nicotianamine Aminotransferase, a Critical Enzyme in Iron Acquisition (Strategy II) in Graminaceous Plants". Plant Physiol. 121 (3): 947–56. doi:10.1104/pp.121.3.947. PMC 59459. PMID 10557244.
- ^ Marschner, Horst (2012). Marschner's Mineral Nutrition of Higher Plants. London Waltham, MA: Academic Press. ISBN 978-0-12-384905-2.