N6-methyl-lysine oxidase

N6-methyl-lysine oxidase
Identifiers
EC no.1.5.3.4
CAS no.37256-28-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

N6-methyl-lysine oxidase (EC 1.5.3.4) is an enzyme that catalyzes the chemical reaction

N6-methyllysine
+ H2O
 
 
O2
H2O2
 
 
 
 

The three substrates of this enzyme are N6-methyllysine, water, and oxygen. Its products are L-lysine, hydrogen peroxide and formaldehyde.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with oxygen as acceptor. The systematic name of this enzyme class is N6-methyl-L-lysine:oxygen oxidoreductase (demethylating). Other names in common use include epsilon-alkyl-L-lysine:oxygen oxidoreductase, N6-methyllysine oxidase, epsilon-N-methyllysine demethylase, epsilon-alkyllysinase, and 6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating).

References

  1. ^ Enzyme 1.5.3.4 at KEGG Pathway Database.
  2. ^ Kim, Sangduk; Benoiton, Leo; Paik, Woon Ki (1964). "Ε-Alkyllysinase". Journal of Biological Chemistry. 239 (11): 3790–3796. doi:10.1016/S0021-9258(18)91206-8. PMID 14257609.