N5-(carboxyethyl)ornithine synthase
| N5-(carboxyethyl)ornithine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.5.1.24 | ||||||||
| CAS no. | 129070-70-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, N5-(carboxyethyl)ornithine synthase (EC 1.5.1.24) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are N5-(L-1-carboxyethyl)-L-ornithine, oxidised nicotinamide adenine dinucleotide phosphate (NADP+), and water. Its products are L-ornithine, reduced NADPH, pyruvic acid, and a proton.[1][2]
Nomenclature
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming). Other names in common use include 5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase, and (L-ornithine-forming).
References
- ^ Enzyme 1.5.1.24 at KEGG Pathway Database.
- ^ Thompson J (June 1989). "N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase from Streptococcus lactis. Purification and partial characterization". The Journal of Biological Chemistry. 264 (16): 9592–601. doi:10.1016/S0021-9258(18)60572-1. PMID 2498334.