N-methylalanine dehydrogenase
| N-methylalanine dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.4.1.17 | ||||||||
| CAS no. | 56379-51-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, N-methylalanine dehydrogenase (EC 1.4.1.17) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are N-methyl-L-alanine, water, and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are pyruvic acid, methylamine, reduced NADPH, and a proton.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating).
References
- ^ Enzyme 1.4.1.17 at KEGG Pathway Database.
- ^ Lin, MC; Wagner, C. (1975). "Purification and characterization of N-methylalanine dehydrogenase". Journal of Biological Chemistry. 250 (10): 3746–3751. doi:10.1016/S0021-9258(19)41461-0. PMID 236301.