Mephenaqualone

Mephenaqualone
Identifiers
  • 8-methoxy-3-(2-methylphenyl)-2-phenylquinazolin-4(3H)-one
Chemical and physical data
FormulaC22H18N2O2
Molar mass342.398 g·mol−1
3D model (JSmol)
  • O=C1N(C(=Nc2c(OC)cccc12)c1ccccc1)c1ccccc1C
  • InChI=InChI=1S/C22H18N2O2/c1-15-9-6-7-13-18(15)24-21(16-10-4-3-5-11-16)23-20-17(22(24)25)12-8-14-19(20)26-2/h3-14H,1-2H3
  • Key:BWXQPJORBOGKST-UHFFFAOYSA-N

Mephenaqualone is an analogue of the sedative and hypnotic drug methaqualone which has been sold as a designer drug. It was reported in Germany in 2025 as a contributor to drug overdose cases but has otherwise been little studied. Anecdotal reports suggest it is significantly more potent than methaqualone with a potency similar to that of benzodiazepine derivatives, but no pharmacological data is available as yet.[1][2][3]

See also

References

  1. ^ Yurchenko R, Yurchenko L, Pavelets Y, Galetskaya I, Navitski M, Piatsetskaya A (July 2024). Psychoactive products market observation. Trend analysis. Recent trends in the field of psychoactive substance identification. p. 11.
  2. ^ "450. Мефенаквалон Раздел I.A. Вещества с подтвержденной структурой" [Mephenaqualone Section I.A. Structure-Confirmed Substances]. AIPSIN (in Russian).
  3. ^ "Warnmeldung. Lebensgefahr durch hochpotente synthetische Opioide in Bayern" [Warning. Life-threatening danger from highly potent synthetic opioids in Bavaria.] (PDF). Bayerische Akademie für Sucht-und Gesundheitsfragen [Bavarian Academy for Addiction and Health Issues] (in German). 2025.
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