Limbal nodule
| Limbal nodule | |
|---|---|
| Limbus | |
| Specialty | Ophthalmology |
A limbal nodule is any nodular lesion at the limbus (junction of the cornea and sclera) of the eye.
The differential diagnosis for a limbal nodule can include:
- Pinguecula
- Early Pterygium
- Foreign body / foreign body granuloma
- Phlycten, an inflamed nodule of lymphoid tissue
- Episcleritis
- Scleritis
- Granuloma
- Limbal dermoid, a kind of choristoma (NB: in other organs dermoid can refer to a teratoma)
- malignant melanoma
- naevus
A 1989 case series of 636 limbal nodules examined over a period of 40 years at the Institute of Ophthalmology in London reported that 351 nodules involved malanocytes with two-thirds being benign nevi. Seventy three lesions were squamous cell carcinomas, and 137 premalignant lesions. Ten percent of the lesions were dermoid nodules.[1]
References
- ^ Garner, Alec (March 1989). "The pathology of tumours at the limbus". Eye. 3 (2): 210–217. doi:10.1038/eye.1989.30.
- Hampton Roy; Daljit Singh; Richard J. Fugo (2010). Ocular Applications of the Fugo Blade. Lippincott Williams & Wilkins. p. 42. ISBN 978-1-60547-888-3.