Leonore Herzenberg

Leonore Herzenberg
Born
Leonore Alderstein

(1935-02-15) February 15, 1935
New York City, US
SpouseLeonard Herzenberg
Children4, including Jana
Scientific career
FieldsImmunology, genetics
InstitutionsStanford University

Leonore Alderstein "Lee" Herzenberg (born February 15, 1935) is an American immunologist, geneticist and professor at Stanford University. Born in New York City, she never received a college degree[1] but studied biology and worked as a researcher alongside her husband Leonard since he began his doctorate at the California Institute of Technology in 1952. At the time, Caltech did not accept women, but although she was registered at Pomona College nearby, Lee was allowed to audit courses and take tests at Caltech.[2]

Leonard and Leonore Herzenberg ran the Herzenberg Laboratory at Stanford together.[3][4][5] Len always supported her role as a leader in science.[6] In 1970 they developed the fluorescence-activated cell sorter[7][8] which revolutionized immunology and cancer biology, and is the basis for purification of adult stem cells.[9] In 1989, they proposed a layered immune system hypothesis for the development of immune cells from stem cells that has been supported by experimental evidence nearly 30 years later.[10][11]

In 1981, the University of Paris gave Lee the title of Doctor of Science.[12] When receiving the Kyoto Prize in 2006, Leonard Herzenberg regretted only that "I only wish it were possible to be shared with my wife and lifelong colleague, Leonore Herzenberg."[9]

Lee and Len Herzenberg had four children: Jana Herzen, formerly Janet Herzenberg, is a singer-songwriter and the founder of Motéma Music; Berri H. Michel owns a bicycle shop in Santa Cruz, California;[13] Rick; and Michael.[2]

References

  1. ^ Douglas Martin (2013). "Leonard Herzenberg, 81, Immunologist Who Revolutionized Research, Dies". New York Times. Retrieved 21 November 2013.
  2. ^ a b Leonard A. Herzenberg and Leonore A. Herzenberg (2004). "Genetics, FACS, Immunology, and Redox: A Tale of Two Lives Intertwined". Annual Review of Immunology. 22. Annual Reviews: 1–31. doi:10.1146/annurev.immunol.22.012703.104727. PMID 15032572.
  3. ^ Herzenberg, Leonard A.; Herzenberg, Leonore A.; Roederer, M. (2013). "A Conversation with Leonard and Leonore Herzenberg". Annual Review of Physiology. 76: 130819115335001. doi:10.1146/annurev-physiol-021113-170355. PMID 23957332.
  4. ^ McCarthy, Pumtiwitt (2012). "The road well traveled together: A joint "Reflections" by Leonore and Leonard Herzenberg". ASBMB Today. Retrieved 26 August 2015.
  5. ^ "Herzenberg Laboratory". Stanford. Archived from the original on 19 March 2005. Retrieved 21 November 2013.
  6. ^ "Video Interview with Mario Roederer and the Herzenbergs". Annual Reviews.
  7. ^ Herzenberg, L. A.; Parks, D.; Sahaf, B.; Perez, O.; Roederer, M.; Herzenberg, L. A. (2002). "The history and future of the fluorescence activated cell sorter and flow cytometry: A view from Stanford". Clinical Chemistry. 48 (10): 1819–1827. doi:10.1093/clinchem/48.10.1819. PMID 12324512.
  8. ^ "The History of the Cell Sorter Interviews". Record Unit 9554. Smithsonian Institution Archives. Retrieved 9 March 2012.
  9. ^ a b Malone, M. A. (2006-06-09). "Stanford scientist wins Kyoto Prize for developing revolutionary cell-sorting technology". Stanford News Center. Retrieved 2026-01-23.
  10. ^ Kobayashi, M; Yoshimoto, M (May 2023). "Multiple waves of fetal-derived immune cells constitute adult immune system". Immunological reviews. 315 (1): 11–30. doi:10.1111/imr.13192. PMID 36929134.
  11. ^ Herzenberg, LA; Herzenberg, LA (22 December 1989). "Toward a layered immune system". Cell. 59 (6): 953–4. doi:10.1016/0092-8674(89)90748-4. PMID 2688900.
  12. ^ "Biography". Stanford. Retrieved 21 November 2013.
  13. ^ "Bicycle Trip". Retrieved 21 November 2013.
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