L2 holin family

The Putative Acholeplasma Phage L2 Holin (L2 Holin) Family (TC# 1.E.59) consists of a putative holin (TC# 1.E.59.1.1; 81 amino acyl residues (aas) and 2 transmembrane segments (TMSs)) and a homologous uncharacterized protein (TC# 1.E.59.1.2; 75 aas and 2 TMSs). These proteins are of particular interest because they may show a link between prokaryotic holins and eukaryotic virus viroporins. While functionally uncharacterized, this putative holin (TC# 1.E.59.1.1) comes up in BLAST searches when members of viroporin families TC# 1.A.95 and TC# 1.A.100 are used as query sequences.[1][2]

See also

Further reading

  • Nieva, José Luis; Madan, Vanesa; Carrasco, Luis (2012). "Viroporins: structure and biological functions". Nature Reviews Microbiology. 10 (8): 563–574. doi:10.1038/nrmicro2820. PMC 7097105.
  • Saier, MH; Reddy, BL (2015). "Holins in bacteria, eukaryotes, and archaea: multifunctional xenologues with potential biotechnological and biomedical applications". J. Bacteriol. 197: 7–17. doi:10.1128/JB.02046-14. PMC 4288690. PMID 25157079..
  • Wang, IN; Smith, DL; Young, R (2000). "Holins: the protein clocks of bacteriophage infections". Annu. Rev. Microbiol. 54: 799–825. doi:10.1146/annurev.micro.54.1.799. PMID 11018145..

References

  1. ^ "TCDB » BLAST". www.tcdb.org. Retrieved 2016-03-31.
  2. ^ "1.E.59. The Putative Acholeplasma Phage L2 Holin (L2 Holin) Family". TCDB. Retrieved 2016-03-30.

As of this edit, this article uses content from "1.E.59. The Putative Acholeplasma Phage L2 Holin (L2 Holin) Family", which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License, but not under the GFDL. All relevant terms must be followed.

This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.