L-lactate dehydrogenase (cytochrome)
| L-lactate dehydrogenase (cytochrome) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.2.3 | ||||||||
| CAS no. | 9078-32-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, L-lactate dehydrogenase (cytochrome) (EC number 1.1.2.3) is an enzyme that catalyzes the chemical reaction
The substrate of this enzyme is (S)-lactic acid, which is acted on by two equivalents of the cofactor, ferricytochrome c, which oxidises the hydroxy group to a keto group, giving pyruvic acid, while the cofactor's iron is reduced.[1][2][3][4]
See also
- D-lactate dehydrogenase (cytochrome) which acts on the enantiomer of the substrate
References
- ^ Enzyme 1.1.2.3 at KEGG Pathway Database.
- ^ Appleby CA, Morton RK (March 1959). "Lactic dehydrogenase and cytochrome b2 of baker's yeast; purification and crystallization". Biochem. J. 71 (3): 492–9. doi:10.1042/bj0710492. PMC 1196822. PMID 13638255.
- ^ Appleby CA, Morton RK (November 1959). "Lactic dehydrogenase and cytochrome b2 of baker's yeast. Enzymic and chemical properties of the crystalline enzyme". Biochem. J. 73 (3): 539–50. doi:10.1042/bj0730539. PMC 1197094. PMID 13793977.
- ^ Bach SJ, Dixon M, Zerfas LG (1946). "Yeast lactic dehydrogenase and cytochrome b(2)". Biochem. J. 40 (2): 229–39. doi:10.1042/bj0400229. PMC 1258326. PMID 16747991.