Kwong Yok Lam

Kwong Yok Lam
鄺沃林
Alma materWah Yan College, Kowloon, University of Hong Kong
Known forResearch on Oral Arsenic Trioxide, Acute Promyelocytic Leukaemia, T-cell lymphoma, Hematopoietic stem cell transplantation, CAR-T
Scientific career
FieldsHaematology
InstitutionsUniversity of Hong Kong
ThesisCytogenetics and molecular genetics of haematological disorders (1995)
Websitehttps://medic.hku.hk/en/Staff/University-Academic-Staff/Prof-KWONG-Yok-Lam/Prof-KWONG-Yok-Lam-Profile

Kwong Yok Lam (Chinese: 鄺沃林) is a Hong Kong haematologist. Prof Kwong is the Chair Professor and Chief of the Division of Haematology, Oncology and Bone Marrow Transplantation at the Department of Medicine, School of Clinical Medicine, the University of Hong Kong. He specialises in haematology and haematopathology. His clinical work focuses on the management of haematological malignancies. His research centres on the molecular pathogenetic pathways and novel treatment modalities in a variety of haematological neoplasms. Prof Kwong has pioneered the development and use of oral arsenic trioxide in the treatment of acute promyelocytic leukaemia and other blood cancers.[1]

Career

Kwong graduated from Wah Yan College, Kowloon in 1976. He obtained his MBBS degree with honours from the Faculty of Medicine of the University of Hong Kong at the top of his class with the John Anderson Gold Medal, CP Fong Gold Medal in Medicine, Digby Memorial Gold Medal in Surgery, Nesta and John Gray Gold Medal in Surgery, and Gordon King Prize in Obstetrics and Gynaecology in 1983.[2] He then received his MRCP in 1986; FRCPath in 1991; FHKCP, FHKAM (Medicine), FHKCPath, and FHKAM (Pathology) in 1993; MD (HK) in 1995, and FRCP (Edin) in 1997.[3]

Kwong Yok-lam, in collaboration with Professor Cyrus Kumana, developed an innovative treatment for acute promyelocytic leukaemia at the University of Hong Kong. This oral arsenic-based drug, arsenic trioxide, created without external funding, has shown remarkable success with a cure rate of 98.2%. The treatment, safer and more cost-effective than intravenous arsenic, has replaced traditional bone marrow transplants in Hong Kong. This breakthrough marks Hong Kong's first drug invention.[4]

In 2025, Kwong along with Dr Harinder Gill and Dr Alfred Tan Keng-Tiong from the University of Hong Kong developed an oral formulation of arsenic trioxide (Oral-ATO; ARSENOL) for the treatment of acute promyelocytic leukaemia.[5]

References

  1. ^ "Yok Lam Kwong". Croucher Foundation. Retrieved 6 February 2025.
  2. ^ "Elixir 1983" (PDF). Elixir 1983. Retrieved 1 September 2025.
  3. ^ "KWONG YOK LAM". The Hong Kong Medical Association. Retrieved 1 September 2025.
  4. ^ "HKU Bulletin". www4.hku.hk. Retrieved 6 February 2025.
  5. ^ Standard, The. "Breakthrough in blood cancer treatment: HKU develops first oral arsenic trioxide". The Standard. Retrieved 12 February 2025.