John H. Edwards

John Hilton Edwards
Born(1928-03-26)26 March 1928
London, England
Died11 October 2007(2007-10-11) (aged 79)
Oxford, England
EducationTrinity Hall, Cambridge[1]
Known forDescription of trisomy 18 syndrome (Edwards syndrome)
SpouseFelicity Claire Toussaint[1]
ChildrenFour: Vanessa, Conrad, Penelope and Matthew[1]
Parents
RelativesA. W. F. Edwards (brother)
Scientific career
FieldsMedical genetics
InstitutionsUniversity of Birmingham, Oxford University, Children's Hospital of Philadelphia[1]
Academic advisorsLancelot Hogben

John Hilton Edwards (26 March 1928 – 11 October 2007) was a British medical geneticist. Edwards reported the first description of a syndrome of multiple congenital malformations associated the presence of an extra chromosome. The extra chromosome belonged to the E group of chromosomes which consisted of chromosomes 16, 17 and 18. The condition is now known as Edwards syndrome or trisomy 18 syndrome.[2]

Life and career

Edwards was the elder son of the surgeon Harold C. Edwards, and the brother of the geneticist and statistician A. W. F. Edwards. He was educated at Uppingham School and Trinity Hall, Cambridge, where some uninspiring courses led him to take only a third in part I of the natural sciences tripos, although he did later graduate with an MB and BChir after further study at Middlesex and Central Middlesex hospitals.[3][4] Early in his career, he worked under Lancelot Hogben, and was sometimes distinguished from his brother as "Hogben's Edwards".

After working for several years as a ship's surgeon and as a population geneticist, Edwards became a consultant paediatrician at hospitals in Philadelphia and Birmingham, England. At the same time, he was first a lecturer, reader and then later Professor of Human Genetics at Birmingham University, remaining in situ until 1979. From 1967 to 1968, he was Visiting Professor of Pediatrics at Cornell University and a Senior Investigator at the New York Blood Center.[4]

In 1979, Edwards was elected to a fellowship of the Royal Society.[1][5] That same year, he was made a Fellow of Keble College, Oxford, and Professor of Genetics at the University of Oxford, where he remained until his retirement in 1995.[4]

References

  1. ^ a b c d e Ferguson-Smith, Malcolm A. (19 April 2017). "John Hilton Edwards. 26 March 1928 – 11 October 2007". Biographical Memoirs of Fellows of the Royal Society. 63: 215–242. doi:10.1098/rsbm.2017.0005. ISSN 0080-4606.
  2. ^ Edwards, J.; Harnden, D. G.; Cameron, A. H.; Crosse, V. M.; Wolf, O. H. (1960). "A New Trisomic Syndrome". The Lancet. 275 (7128): 787–790. doi:10.1016/S0140-6736(60)90675-9. PMID 13819419.
  3. ^ Ferguson-Smith, Malcolm A., "Edwards, John Hilton (1928–2007)", Oxford Dictionary of National Biography, Oxford University Press, 2013; online edition, January 2011. Retrieved 23 October 2025. (subscription required)
  4. ^ a b c "Edwards, Prof. John Hilton". Who Was Who 1920–2008. Oxford University Press. December 2008. Retrieved 21 February 2010.
  5. ^ Royal Society Certificate of Election

Further information

Obituaries