Independent clinical trials

An independent clinical trial is a clinical trial promoted by scientific organizations and funded by public or charitable money, research centres or voluntary groups.[1][2]

A large number of clinical research questions that are of little or no interest to commercial sponsors but still need to be addressed, given their importance to public health and to improving diagnosis and therapy for groups of patients of varying size, such as questions about the best treatment options for a particular illness.[3] This is contrast with most clinican studies, which are funded by pharmaceutical companies on drugs and devices. These are product-oriented, aiming to test the benefits of a particular treatment.[4][5]

Independent clinical studies are of key importance for improving the effectiveness, safety and cost/benefit balance, such as the long-term risks and rare adverse reactions to treatments, comparing the available treatment options, evaluating improvements in quality of life or in follow-up of procedures and rehabilitation strategies. Investing in independent clinical research brings dividends for society in terms of reducing the impact of diseases, improving care strategies, and containing costs of health systems.[6]

References

  1. ^ Cocconi, G (2002). "Independent clinical trials: a commentary". Tumori. 88 (2): 85–8. doi:10.1177/030089160208800201. PMID 12088263. S2CID 38607874.
  2. ^ European Science foundation. Forward Look. Investigator-Driven Clinical Trials (PDF) (Report). Archived from the original (PDF) on 2015-09-24. Retrieved 2014-11-04.
  3. ^ Moses, H III; Dorsey, ER; Matheson, DH; Thier, SO (2005). "Financial anatomy of biomedical research". JAMA. 294 (11): 1333–42. doi:10.1001/jama.294.11.1333. PMC 3118092. PMID 16174691.
  4. ^ European Commission. Q&A: New rules for clinical trials conducted in the EU (Report).
  5. ^ Chalmers, I (2006). "Biomedical research: are we getting value for money?". Significance. 3 (4): 172–5. doi:10.1111/j.1740-9713.2006.00200.x.
  6. ^ Remuzzi, G; Schieppati, A; Boissel, GP; Garattini, S; Horton, R (2004). "Independent clinical research in Europe". The Lancet. 364 (9446): 1723–26. doi:10.1016/s0140-6736(04)17360-1. PMID 15530634. S2CID 42512035.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.