Sodium polydihydroxyphenylene thiosulfonate

Hypoxen
Identifiers
  • Sodium polydihydroxyphenylene thiosulfonate
CAS Number
UNII
Chemical and physical data
FormulaC12+6nH9+4nNaO7+2nS2

Sodium polydihydroxyphenylene thiosulfonate (гипоксен, Hypoxen) is under laboratory studies in Russia as a potential regulator of cell metabolism.[1]

It is registered in Russia as an antihypoxic agent, but has not been subjected to any clinical trials meeting internationally accepted standards, and has no regulatory approval as a prescription drug outside Russia and some former Soviet states.

It has been identified in tests on athletes in competition, such as Kamila Valieva, a Russian figure-skater competing at the 2022 Winter Olympics, but is not itself banned in international competitions, as of 2022.[2][3]

Potential abuse in sports

Although called an "oxygen booster" in public media to imply its potential to "increase endurance and reduce fatigue",[4] there is no scientific evidence it has this property, and it is not used in conventional cardiology as a therapy for treating heart disease.[5]

Hypoxen is sold online without a prescription, mainly from Russian websites, and does not appear to be sold in health stores in the United States.[5] Hypoxen is not listed on the prohibited substance list of the World Anti-Doping Agency.[5] In 2017, the United States Anti-Doping Agency applied to have hypoxen banned from athletic competitions, but the ban was not implemented.[4]

See also

References

  1. ^ Novikov VE, Levchenkova OS, Ivantsova EN, Vorobieva VV (2019). "Mitochondrial dysfunctions and antihypoxants". Reviews on Clinical Pharmacology and Drug Therapy. 17 (4): 31–42. doi:10.17816/RCF17431-42. S2CID 214116979.
  2. ^ Schad T (16 February 2022). "What we know now: The latest developments in Kamila Valieva's doping case". USA Today. Retrieved 18 February 2022.
  3. ^ Panja T (15 February 2022). "Kamila Valieva's sample included three substances sometimes used to help the heart. Only one is banned". The New York Times. Retrieved 16 February 2022.
  4. ^ a b Wang S, McCarthy S, Ritchie H (16 February 2022). "Kamila Valieva: US anti-doping chief questions skater's drug regimen to 'increase endurance and reduce fatigue'". CNN. Retrieved 18 February 2022.
  5. ^ a b c Kolata G (15 February 2022). "Cardiologists question the utility of the drugs found in Valieva's blood". The New York Times. Retrieved 16 February 2022.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.