Hedonal
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| Formula | C6H13NO2 |
| Molar mass | 131.175 g·mol−1 |
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Hedonal is an anesthetic agent first synthesised in 1899 and developed as a medicine in Russia in the 1920s. It is the carbamate derivative of 2-pentanol. It was found to be safer and more effective than agents such as chloroform and diethyl ether which were commonly used as anesthetics at the time, but fell into disuse following the introduction of the barbiturates.[1][2][3][4][5][6]
See also
References
- ^ Dresser H (1900). "A new hypnotic of the urethane group". Munchen Med Wochen. 40: 1310.
- ^ Sofronov NS (1952). "[Experimental studies on pharmacological substances in sleep therapy. 1. Hypnotic effect of barbamyl, hedonal, narcolan, chloral hydrate, ethyl alcohol and of their combinations]". Trudy - Institut Fiziologii imeni I. P. Pavlova. 1: 243–250. PMID 13187639.
- ^ Kissin I, Wright AJ (August 1988). "The introduction of hedonal: a Russian contribution to intravenous anesthesia". Anesthesiology. 69 (2): 242–245. doi:10.1097/00000542-198808000-00014. PMID 3044190.
- ^ Budko AA, Shabunin AV, Serikov VV (September 2000). "[The history of the "Russian method" of anesthesia]". Voenno-Meditsinskii Zhurnal. 321 (9): 78–81. PMID 11077538.
- ^ Ball C, Westhorpe R (February 2001). "Early intravenous anaesthesia". Anaesthesia and Intensive Care. 29 (1): 3. doi:10.1177/0310057X0102900201. PMID 11261906.
- ^ Maslov OK (2007). "[Forgotten names in anesthesiology]". Anesteziologiia I Reanimatologiia (2): 5. PMID 17563991.