Glycine dehydrogenase (cyanide-forming)
| glycine dehydrogenase (cyanide-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.4.99.5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, glycine dehydrogenase (cyanide-forming) (EC 1.4.99.5) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are glycine and an electron acceptor. Its products are hydrogen cyanide, carbon dioxide, and reduced acceptor.[1][2][3][4][5]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with other acceptors. The systematic name of this enzyme class is glycine:acceptor oxidoreductase (hydrogen-cyanide-forming). Other names in common use include hydrogen cyanide synthase, and HCN synthase.
References
- ^ Enzyme 1.4.99.5 at KEGG Pathway Database.
- ^ Wissing F (1975). "Cyanide production from glycine by a homogenate from a Pseudomonas species". J. Bacteriol. 121 (2): 695–9. doi:10.1128/jb.121.2.695-699.1975. PMC 245984. PMID 234422.
- ^ Castric PA (1977). "Glycine metabolism by Pseudomonas aeruginosa: hydrogen cyanide biosynthesis". J. Bacteriol. 130 (2): 826–31. doi:10.1128/jb.130.2.826-831.1977. PMC 235287. PMID 233722.
- ^ Haas D; Blumer, C; Von Schroetter, C; Gaia, V; Défago, G; Keel, C; Haas, D (1998). "Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0". J. Bacteriol. 180 (12): 3187–96. doi:10.1128/JB.180.12.3187-3196.1998. PMC 107821. PMID 9620970.
- ^ Blumer C, Haas D (2000). "Mechanism, regulation, and ecological role of bacterial cyanide biosynthesis". Arch. Microbiol. 173 (3): 170–7. Bibcode:2000ArMic.173..170B. doi:10.1007/s002039900127. PMID 10763748.