Glutathione—homocystine transhydrogenase

Glutathione—homocystine transhydrogenase (EC 1.8.4.1) is an enzyme that catalyzes the chemical reaction

The substrates of this enzyme are glutathione and homocystine. Its products are glutathione disulfide and homocysteine.[1][2]

Glutathione—homocystine transhydrogenase
Identifiers
EC no.1.8.4.1
CAS no.9029-40-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is glutathione:homocystine oxidoreductase. This enzyme participates in methionine metabolism and glutathione metabolism.

References

  1. ^ Enzyme 1.8.4.1 at KEGG Pathway Database.
  2. ^ Racker, E. (December 1955). "Glutathione-homocystine transhydrogenase". Journal of Biological Chemistry. 217 (2): 867–874. doi:10.1016/s0021-9258(18)65951-4. ISSN 0021-9258. PMID 13271447.