Fructose 5-dehydrogenase (NADP+)
| fructose 5-dehydrogenase (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.124 | ||||||||
| CAS no. | 37250-53-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, fructose 5-dehydrogenase (NADP+) (EC 1.1.1.124) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-fructose (shown in its keto form) and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). ts products are 5-dehydro-D-fructose, reduced NADPH, and a proton.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-fructose:NADP+ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase (NADP+), 5-keto-D-fructose reductase (NADP+), fructose 5-(nicotinamide adenine dinucleotide phosphate), dehydrogenase, D-(-)fructose:(NADP+) 5-oxidoreductase, and fructose 5-dehydrogenase (NADP+).
References
- ^ Enzyme 1.1.1.124 at KEGG Pathway Database.
- ^ Ameyama M, Matsushita K, Shinagawa E, Adachi O (1981). "5-keto-D-Fructose reductase of Gluconobacter industrius Purification, crystallization and properties". Agric. Biol. Chem. 45 (4): 863–869. doi:10.1271/bbb1961.45.863.
- ^ Avigad G, Englard S, Pifko S (1966). "5-Keto-D-fructose. IV. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from Gluconobacter cerinus". J. Biol. Chem. 241 (2): 373–8. doi:10.1016/S0021-9258(18)96926-7. PMID 4379259.