Eran Segal

This article is about a biologist. For the heavy metal guitarist, see Aborted.
Eran Segal
ערן סגל
Born (1973-11-15) November 15, 1973
Alma materStanford University
Tel Aviv University
AwardsFellow, ISCB (2026)[1]
Overton Prize (2007)[2]
Scientific career
FieldsComputational biology
Systems biology
Microbiome
Personalized medicine
InstitutionsRockefeller University
Weizmann Institute of Science
Mohamed bin Zayed University of Artificial Intelligence
ThesisRich Probabilistic Models for Genomic Data (2004)
Daphne Koller[3]

Eran Segal (Hebrew: ערן סגל; born 15 November 1973) is a computational biologist professor at the Weizmann Institute of Science.[3] He works on developing quantitative models for all levels of gene regulation,[4] including transcription, chromatin, and translation.[5][6][7] In 2006, Segal and Jonathan Widom of Northwestern University published a model of nucleosome positioning along DNA in Nature.[8] Segal also works as an epidemiologist.[9]

Education

Segal earned a BA in Computer Science and Economics from Tel Aviv University in 1998.[3]

He earned a PhD from Stanford University in 2004 advised by Daphne Koller with a dissertation titled: Rich Probabilistic Models for Genomic Data.[10] In support of his graduate study at Stanford he received a Fulbright Foreign Student Program grant in 1999.[11]

Career

After completing his Ph.D., Segal held a postdoctoral research position at Rockefeller University from 2004 to 2005 before joining the Departments of Computer Science and Applied Mathematics and of Molecular Cell Biology[12] at the Weizmann Institute of Science in 2005.[13]

A 2015 study in Cell by Segal and colleagues showed that glucose responses to identical foods vary substantially between individuals.[14][15] In 2018, Segal launched the Human Phenotype Project at the Weizmann Institute. The longitudinal cohort study collects genomic, microbiome, continuous glucose monitoring, imaging, and lifestyle data from participants across 17 body systems over a 25-year period, with more than 28,000 participants enrolled as of 2025.[16][17]

As of 2025, Segal serves as Acting Dean of the School of Digital Public Health and Professor of Computational Biology at the Mohamed bin Zayed University of Artificial Intelligence (MBZUAI).[18][19]

Awards and honors

References

  1. ^ a b "April 21, 2026: ISCB Announces the 2026 Class of Fellows!". International Society for Computational Biology. 21 April 2026. Retrieved 12 May 2026.
  2. ^ a b Maisel, M. (2007). "ISCB Honors Temple F. Smith and Eran Segal". PLOS Computational Biology. 3 (6): e128. Bibcode:2007PLSCB...3..128M. doi:10.1371/journal.pcbi.0030128. PMC 1904388. PMID 17604447.
  3. ^ a b c "Eran Segal biography". Weizmann Institute of Science. Retrieved 27 April 2026.
  4. ^ Kaplan, N.; Moore, I. K.; Fondufe-Mittendorf, Y.; Gossett, A. J.; Tillo, D.; Field, Y.; Leproust, E. M.; Hughes, T. R.; Lieb, J. D.; Widom, J.; Segal, E. (2008). "The DNA-encoded nucleosome organization of a eukaryotic genome". Nature. 458 (7236): 362–366. Bibcode:2009Natur.458..362K. doi:10.1038/nature07667. PMC 2658732. PMID 19092803.
  5. ^ Segal, E.; Fondufe-Mittendorf, Y.; Chen, L.; Thåström, A.; Field, Y.; Moore, I. K.; Wang, J. P. Z.; Widom, J. (2006). "A genomic code for nucleosome positioning". Nature. 442 (7104): 772–778. Bibcode:2006Natur.442..772S. doi:10.1038/nature04979. PMC 2623244. PMID 16862119.
  6. ^ Segal, E.; Shapira, M.; Regev, A.; Pe'er, D.; Botstein, D.; Koller, D.; Friedman, N. (2003). "Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data". Nature Genetics. 34 (2): 166–176. doi:10.1038/ng1165. PMID 12740579. S2CID 6146032.
  7. ^ Segal, E.; Widom, J. (2009). "From DNA sequence to transcriptional behaviour: A quantitative approach". Nature Reviews Genetics. 10 (7): 443–456. doi:10.1038/nrg2591. PMC 2719885. PMID 19506578.
  8. ^ Wade, Nicholas (25 July 2006). "Scientists Say They've Found a Code Beyond Genetics in DNA". The New York Times. Retrieved 27 April 2026.
  9. ^ "Epidemiologist estimates nearly half of Israeli population caught Omicron". Times of Israel. February 19, 2022. Retrieved 13 September 2022.
  10. ^ Segal, Eran (2004). Rich Probabilistic Models for Genomic Data (PhD thesis). Stanford University.
  11. ^ "Grantee Directory". Fulbright Foreign Student Program. Institute of International Education. Retrieved 1 June 2026. Eran Segal — Foreign Grantee; Stanford University; California; Computer Science; Israel; 1999
  12. ^ "Prof. Eran Segal". Weizmann Institute of Science. Retrieved 22 April 2026.
  13. ^ "Eran Segal". Israel Institute for Advanced Studies. Hebrew University of Jerusalem. Retrieved 22 April 2026.
  14. ^ Zeevi, David; Korem, Tal; Zmora, Niv; et al. (2015). "Personalized Nutrition by Prediction of Glycemic Responses". Cell. 163 (5): 1079–1094. doi:10.1016/j.cell.2015.11.001. PMID 26590418.
  15. ^ Murphy, Kate (11 January 2016). "A Personalized Diet, Better Suited to You". The New York Times. Retrieved 27 April 2026.
  16. ^ Siegel-Itzkovich, Judy (10 August 2025). "An AI model from Weizmann Institute can predict your future health – and help you change it". The Jerusalem Post. Retrieved 27 April 2026.
  17. ^ Reicher, Lee; Shilo, Smadar; Godneva, Anastasia; Lutsker, Guy; et al. (2025). "Deep phenotyping of health–disease continuum in the Human Phenotype Project". Nature Medicine. 31 (9): 3191–3203. doi:10.1038/s41591-025-03790-9. PMID 40665053.
  18. ^ "Can AI-powered digital twins revolutionize healthcare? This MBZUAI professor thinks so". Fast Company Middle East. 8 September 2025. Retrieved 27 April 2026.
  19. ^ "MBZUAI opens applications for first Master's and Ph.D. cohorts in computational biology". Zawya. 26 November 2025. Retrieved 27 April 2026.
  20. ^ "Eran Segal". EMBO People. European Molecular Biology Organization. Retrieved 22 April 2026.
  21. ^ "Bruno Laureates". Israel Institute for Advanced Studies. Hebrew University of Jerusalem. Retrieved 22 April 2026.
  22. ^ "ERC Consolidator Grants 2013 Results: List of Principal Investigators" (PDF). European Research Council. 18 February 2014. Retrieved 2 June 2026.
  23. ^ "Discovering microbiome-based disease risk factors". CORDIS. European Commission. Retrieved 2 June 2026.
  24. ^ "List of ERC-funded research projects related to coronavirus". European Research Council. European Commission. Retrieved 2 June 2026.
  25. ^ "Eighteen young scientists join EMBO Young Investigator network". CORDIS. Publications Office of the European Union. 23 October 2007. Retrieved 1 June 2026.
  26. ^ "RECOMB Awards". RECOMB Conference Series. Retrieved 22 April 2026.
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