Encofosbuvir

Encofosbuvir
Clinical data
Trade names英强布韦
Legal status
Legal status
  • Rx in China
Identifiers
  • [3-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-3-methyl-5-[[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxymethyl]oxolan-2-yl]-2,6-dioxopyrimidin-1-yl]methyl (2S)-2-(methoxycarbonylamino)-4-methylsulfanylbutanoate
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC30H42FN4O13PS
Molar mass748.71 g·mol−1
3D model (JSmol)
  • C[C@]1(F)[C@@H](O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OC(C)C)=O)C)=O)[C@H]1O)N3C(=O)N(COC([C@@H](NC(OC)=O)CCSC)=O)C(=O)C=C3
  • InChI=1S/C30H42FN4O13PS/c1-18(2)46-25(38)19(3)33-49(42,48-20-10-8-7-9-11-20)45-16-22-24(37)30(4,31)27(47-22)34-14-12-23(36)35(29(34)41)17-44-26(39)21(13-15-50-6)32-28(40)43-5/h7-12,14,18-19,21-22,24,27,37H,13,15-17H2,1-6H3,(H,32,40)(H,33,42)/t19-,21-,22+,24+,27+,30+,49-/m0/s1
  • Key:GAHCKEWMXZYJAZ-VBWBMHESSA-N

Encofosbuvir is an antiviral drug used to treat hepatitis C virus (HCV). In China, encofosbuvir is approved for use in combination with netanasvir for the treatment of adult patients with chronic HCV genotypes 1, 2, 3, or 6, who are either treatment-naive or have been previously treated with interferon.[1]

References

  1. ^ "Netanasvir Phosphate Capsules Approved for Marketing by China NMPA". National Medical Products Administration. 2025-06-11.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.