Delta1-piperideine-2-carboxylate reductase

delta1-piperideine-2-carboxylate reductase
Identifiers
EC no.1.5.1.21
CAS no.52037-88-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, Delta1-piperideine-2-carboxylate reductase (EC 1.5.1.21) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
 
H+
 
1-piperideine-2-carboxylic acid
 

The two substrates of this enzyme are (–)-pipecolic acid and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are 1-piperideine-2-carboxylic acid, reduced NADPH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-pipecolate:NADP+ 2-oxidoreductase. Other names in common use include 1,2-didehydropipecolate reductase, P2C reductase, and 1,2-didehydropipecolic reductase. This enzyme participates in lysine degradation.

References

  1. ^ Enzyme 1.5.1.21 at KEGG Pathway Database.
  2. ^ Payton CW, Chang YF (1982). "delta1-piperideine-2-carboxylate reductase of Pseudomonas putida". J. Bacteriol. 149 (3): 864–71. doi:10.1128/jb.149.3.864-871.1982. PMC 216472. PMID 6801013.