D-xylose 1-dehydrogenase
| D-xylose 1-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.175 | ||||||||
| CAS no. | 62931-20-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, D-xylose 1-dehydrogenase (EC 1.1.1.175) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-xylose, shown in its open-chain aldehydo form, and oxidised nicotinamide adenine dinucleotide (NAD+). Its 3 products are D-xylono-1,5-lactone, reduced NADH, and a proton.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-xylose:NAD+ 1-oxidoreductase. Other names in common use include NAD+-D-xylose dehydrogenase, D-xylose dehydrogenase, and (NAD+)-linked D-xylose dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.
See also
- D-xylose 1-dehydrogenase (NADP+) which catalyses the same reaction using the cofactor nicotinamide adenine dinucleotide phosphate
References
- ^ Enzyme 1.1.1.175 at KEGG Pathway Database.
- ^ Yamanaka K, Gino M, Kaneda R (1977). "A specific NAD-D-xylose dehydrogenase from Arthrobacter sp". Agric. Biol. Chem. 41 (8): 1493–1499. doi:10.1271/bbb1961.41.1493.