D-nopaline dehydrogenase
| D-nopaline dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.5.1.19 | ||||||||
| CAS no. | 64763-57-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, D-nopaline dehydrogenase (EC 1.5.1.19) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are nopaline, oxidised nicotinamide adenine dinucleotide phosphate (NADP+), and water. Its products are L-arginine, reduced NADPH, α-ketoglutaric acid and a proton.[1] Nopaline is a member of the class of compounds called opines.[2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming). Other names in common use include D-nopaline synthase, nopaline dehydrogenase, nopaline synthase, NOS, 2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase, and (L-arginine-forming). This enzyme participates in arginine and proline metabolism.
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