D-galactose 1-dehydrogenase
| d-galactose 1-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.48 | ||||||||
| CAS no. | 9028-54-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a d-galactose 1-dehydrogenase (EC 1.1.1.48) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-galactose and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are D-galactono-1,4-lactone, reduced NADH, and a proton.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is d-galactose:NAD+ 1-oxidoreductase. Other names in common use include d-galactose dehydrogenase, beta-galactose dehydrogenase, and NAD+-dependent d-galactose dehydrogenase. This enzyme participates in galactose metabolism.
References
- ^ Enzyme 1.1.1.48 at KEGG Pathway Database.
- ^ De Ley J, Doudoroff M (1957). "The metabolism of D-galactose in Pseudomonas saccharophila". J. Biol. Chem. 227 (2): 745–57. doi:10.1016/S0021-9258(18)70755-2. PMID 13462997.
- ^ Hu, ASL; Cline AL (1964). "The regulation of some sugar dehydrogenases in a pseudomonad". Biochim. Biophys. Acta. 93 (2): 237–245. doi:10.1016/0304-4165(64)90371-x. PMID 14251301.