Cyclohexylamine oxidase

cyclohexylamine oxidase
Identifiers
EC no.1.4.3.12
CAS no.63116-97-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction

+ H2O
 
 
O2
H2O2
O2
H2O2
 
+ NH3
 

The three substrates of this enzyme are cyclohexylamine, water, and oxygen. Its products are cyclohexanone, hydrogen peroxide, and ammonia.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is cyclohexylamine:oxygen oxidoreductase (deaminating). This enzyme participates in caprolactam degradation. It employs one cofactor, FAD.

References

  1. ^ Enzyme 1.4.3.12 at KEGG Pathway Database.
  2. ^ Tokieda T, Niimura T, Takamura F, Yamaha T (April 1977). "Purification and some properties of cyclohexylamine oxidase from a Pseudomonas sp". J. Biochem. 81 (4). Tokyo: 851–8. doi:10.1093/oxfordjournals.jbchem.a131549. PMID 18451.