Chondroitin

A chondroitin, as the sulfate, is a component of bamacan, a proteoglycan (sugar-protein conjugate) that comprises some membranes.[1] Chondroitin is a chondrin derivative.[2]

Types include:

Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis.[3] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine.[3] Chondroitin's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules.[4] The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal.[4] Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery.[5] However, the effectiveness of the drugs is still doubtful.[4]

References

  1. ^ Iozzo, Renato V. (1998). "MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function". Annual Review of Biochemistry. 67: 609–652. doi:10.1146/annurev.biochem.67.1.609. PMID 9759499.
  2. ^ Chondroitin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  3. ^ a b Vasiliadis, Haris S; Tsikopoulos, Konstantinos (2017). "Glucosamine and chondroitin for the treatment of osteoarthritis". World Journal of Orthopedics. 8 (1): 1–11. doi:10.5312/wjo.v8.i1.1. ISSN 2218-5836. PMC 5241539. PMID 28144573.
  4. ^ a b c Tavakol, Kamran. "Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis". Physical Therapy. 80 (10): 1049.
  5. ^ Zhu, Xiaoyue; Sang, Lingli; Wu, Dandong; Rong, Jiesheng; Jiang, Liying (December 2018). "Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials". Journal of Orthopaedic Surgery and Research. 13 (1): 170. doi:10.1186/s13018-018-0871-5. ISSN 1749-799X. PMC 6035477. PMID 29980200.
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