Cedramber

Cedramber
Names
	IUPAC name (8α)-8-Methoxycedrane
	Other names octahydro-6-methoxy-3,6,8,8-tetramethyl-(3R,3aS,6R,7R,8aS)-1H-3a,7-Methanoazulene; Cedryl methyl ether; Methyl Cedryl Ether; (1S,2R,5S,7R,8R)-8-methoxy-2,6,6,8-tetramethyltricyclo[5.3.1.01,5]undecane;
Identifiers
CAS Number	67874-81-1;
3D model (JSmol)	Interactive image;
ChemSpider	9260942;
ECHA InfoCard	100.061.354
EC Number	267-510-5;
PubChem CID	11085796;
UNII	84S7T555CV;
CompTox Dashboard (EPA)	DTXSID90886996 ;
	InChI InChI=1S/C16H28O/c1-11-6-7-12-14(2,3)13-10-16(11,12)9-8-15(13,4)17-5/h11-13H,6-10H2,1-5H3/t11-,12+,13-,15-,16+/m1/s1 Key: HRGPYCVTDOECMG-RHBQXOTJSA-N;
	SMILES C[C@@H]1CC[C@@H]2[C@]13CC[C@@]([C@H](C3)C2(C)C)(C)OC;
Properties
Chemical formula	C16H28O
Molar mass	236.399 g/mol
Appearance	Colourless liquid
Odor	woody
Density	1.0±0.1 g/cm3
Boiling point	259 °C (498 °F; 532 K)
Vapor pressure	0.0±0.5 kPa (20 °C)
Refractive index (nD)	1.496 (10.5 °C)
Hazards
	GHS labelling:[1]
Pictograms
Signal word	Warning
Hazard statements	H315, H317, H319, H332, H410
Precautionary statements	P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P317, P321, P333+P317, P337+P317, P362+P364, P391, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

(8α)-8-Methoxycedrane (also called Cedramber) is a fragrance compound.^[1] According to International Flavors & Fragrances Inc., it has a woody, ambergris odor.^[2]

Preparation

Cedryl methyl ether can be prepared from cedrol. Cedrol reacts with sodium hydride to form the sodium salt, which can be methylated by dimethyl sulfate.^[3]

All endpoints were cleared in a safety assessment by the Research Institute for Fragrance Materials.^[4]

^ "ChemSpider".
^ "IFF".
^ Zhu, Guangyong; Xiao, Zuobing (2022-12-28). "Flavors and Fragrances: Structure of Various Flavors with Food Ingredients". Flavors and Fragrances in Food Processing: Preparation and Characterization Methods. ACS Symposium Series. Vol. 1433. American Chemical Society. p. 48. ISBN 9780841297319. Retrieved 2026-04-03.
^ Api, A. M.; Bartlett, A.; Belsito, D.; Botelho, D.; Bruze, M.; Bryant-Friedrich, A.; Burton, G. A.; Cancellieri, M. A.; Chon, H.; Cronin, M.; Crotty, S.; Dagli, M. L.; Dekant, W.; Deodhar, C.; Farrell, K. (2026-04-01). "RIFM fragrance ingredient safety assessment, cedryl methyl ether, CAS Registry Number 67874-81-1". Food and Chemical Toxicology. RIFM Fragrance Material Safety Assessments. 210 115973. doi:10.1016/j.fct.2026.115973. ISSN 0278-6915.