Bile acid CoA-transferase
| Bile acid CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.3.25 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In enzymology, a bile acid CoA-transferase (EC 2.8.3.25) is an enzyme that catalyzes the chemical reactions
- lithocholoyl-CoA + cholate choloyl-CoA + lithocholate
- deoxycholoyl-CoA + cholate choloyl-CoA + deoxycholate
This enzyme is involved in the removal of the CoA moiety from lithocholoyl-CoA and deoxycholoyl-CoA to form lithocholate and deoxycholate respectively.
This enzyme belongs to the family of transferases, specifically those acting on CoA. The systematic name of this enzyme is lithocholoyl-CoA:cholate CoA-transferase.
References
- Ye HQ, Mallonee DH, Wells JE, Bjorkhem I, Hylemon PB (1999). "The bile acid-inducible baiF gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A hydrolase". J. Lipid Res. 40 (1): 17–23. doi:10.1016/S0022-2275(20)33335-6. PMID 9869646.