Benzaldehyde dehydrogenase (NADP+)
| benzaldehyde dehydrogenase (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.7 | ||||||||
| CAS no. | 9028-89-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a benzaldehyde dehydrogenase (NADP+) (EC 1.2.1.7) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are benzaldehyde, oxidised nicotinamide adenine dinucleotide phosphate (NADP+), and water. Its products are benzoic acid, reduced NADPH, and a proton.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NADP+ oxidoreductase. Other names in common use include NADP+-linked benzaldehyde dehydrogenase, and benzaldehyde dehydrogenase (NADP+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation.
References
- ^ Enzyme 1.2.1.7 at KEGG Pathway Database.
- ^ Gunsalus, C. F.; Stanier, R. Y.; Gunsalus, I. C. (1953). "The Enzymatic Conversion of Mandelic Acid to Benzoic Acid III". Journal of Bacteriology. 66 (5): 548–553. doi:10.1128/jb.66.5.548-553.1953. PMC 317432. PMID 13108854.
- ^ Stachow CS, Stevenson IL, Day D (1967). "Purification and properties of nicotinamide adenine dinucleotide phosphate-specific benzaldehyde dehydrogenase from Pseudomonas". J. Biol. Chem. 242 (22): 5294–300. doi:10.1016/S0021-9258(18)99427-5. PMID 4383635.