Benzaldehyde dehydrogenase (NAD+)

benzaldehyde dehydrogenase (NAD+)
Identifiers
EC no.1.2.1.28
CAS no.37250-93-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, benzaldehyde dehydrogenase (NAD+) (EC 1.2.1.28) is an enzyme that catalyzes the chemical reaction

+ NAD+
 
 
H2O
H+
H2O
H+
 
 

The three substrates of this enzyme are benzaldehyde, oxidised nicotinamide adenine dinucleotide (NAD+), and water. Its products are benzoic acid, reduced NADH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NAD+ oxidoreductase. Other names in common use include benzaldehyde (NAD+) dehydrogenase, and benzaldehyde dehydrogenase (NAD+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation.

References

  1. ^ Enzyme 1.2.1.28 at KEGG Pathway Database.
  2. ^ Gunsalus, C. F.; Stanier, R. Y.; Gunsalus, I. C. (1953). "The Enzymatic Conversion of Mandelic Acid to Benzoic Acid III". Journal of Bacteriology. 66 (5): 548–553. doi:10.1128/jb.66.5.548-553.1953. PMC 317432. PMID 13108854.