Acetic acid (medical use)

Acetic acid
Chemical formula of acetic acid
Clinical data
Pronunciationa-SEE-tik
Trade namesAcetasol, Vasotate, Domeboro Otic, others
Other namesVinegar
AHFS/Drugs.comMonograph
License data
Routes of
administration
ear drops, irrigation, by mouth
ATC code
Legal status
Legal status
Identifiers
  • acetic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
PDB ligand
Chemical and physical data
FormulaC2H4O2
Molar mass60.052 g·mol−1
3D model (JSmol)
  • CC(=O)O
  • InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
  • Key:QTBSBXVTEAMEQO-UHFFFAOYSA-N

Acetic acid, which at low concentrations is known as vinegar, is an acid used to treat a number of conditions.

Definition and medical uses

As an eardrop it is used to treat infections of the ear canal.[1] It may be used with an ear wick.[2] As a liquid it is used to flush the bladder in those who have a urinary catheter in an attempt to prevent infection or blockage.[3] As a gel it may be used to adjust the pH of the vagina.[4] It may also be applied to the cervix to help detect cervical cancer during screening.[5]

Side effects may include burning at the site of application.[6] Allergic reactions may rarely occur.[6] Use is not recommended in the ear in people who have a hole in the eardrum.[7] It works against both bacterial and fungal causes of external ear infections.[7]

History and culture

Acetic acid has been used medically since the time of Ancient Egypt.[8][9] It is on the World Health Organization's List of Essential Medicines.[10] Acetic acid is more commonly used for external ear infections in the developing world than the developed.[11]

References

  1. ^ "Acetic acid (otic) medical facts from Drugs.com". www.drugs.com. Archived from the original on 18 January 2017. Retrieved 14 January 2017.
  2. ^ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 252. ISBN 978-1-284-05756-0.
  3. ^ "Acetic Acid". The American Society of Health-System Pharmacists. Archived from the original on 18 January 2017. Retrieved 8 January 2017.
  4. ^ "Acetic acid gel: Indications, Side Effects, Warnings - Drugs.com". www.drugs.com. Archived from the original on 18 January 2017. Retrieved 14 January 2017.
  5. ^ Fokom-Domgue J, Combescure C, Fokom-Defo V, Tebeu PM, Vassilakos P, Kengne AP, Petignat P (July 2015). "Performance of alternative strategies for primary cervical cancer screening in sub-Saharan Africa: systematic review and meta-analysis of diagnostic test accuracy studies". BMJ. 351 h3084. doi:10.1136/bmj.h3084. PMC 4490835. PMID 26142020.
  6. ^ a b "Acetic acid otic Side Effects in Detail - Drugs.com". www.drugs.com. Archived from the original on 18 January 2017. Retrieved 14 January 2017.
  7. ^ a b "Acetic Acid - FDA prescribing information, side effects and uses". www.drugs.com. Archived from the original on 18 January 2017. Retrieved 14 January 2017.
  8. ^ Cook L (2005). "Supplements: Use Often for Health". The Beginner's Guide to Natural Living: How to Cultivate a More Natural Lifestyle to Lose Weight, Prevent Degenerative Disease, Improve Your Energy and Attain Vibrant Health. EcoVision Communications. p. 107. ISBN 978-0-9755361-8-6. Archived from the original on 16 January 2017.
  9. ^ Cumston CG (2013). "Hindu Medicine. Chaldean And Persian Medicine". The History of Medicine. Routledge. p. Chapter 2. ISBN 978-1-136-19425-2. Archived from the original on 16 January 2017.
  10. ^ The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. 2023. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
  11. ^ Marchick M (2016). "Ear Pain and Cerumen Impaction". In Desai B, Desai A (eds.). Primary Care for Emergency Physicians. Springer. p. 36. ISBN 978-3-319-44360-7. Archived from the original on 16 January 2017.