4-Methylaminobutanoate oxidase (formaldehyde-forming)

4-methylaminobutanoate oxidase (formaldehyde-forming)
Identifiers
EC no.1.5.3.19
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

4-methylaminobutanoate oxidase (formaldehyde-forming) (EC 1.5.3.19, mabO (gene)) is an enzyme with systematic name 4-methylaminobutanoate:oxygen oxidoreductase (formaldehyde-forming). This enzyme catalyses the following chemical reaction

4-(methylamino)butyric acid
+ H2O
 
 
O2
H2O2
O2
H2O2
 
 

This enzyme is a flavoprotein containing flavin adenine dinucleotide.[1] It is involved in the metabolism of nicotine in Arthrobacter nicotinovorans.[2]

References

  1. ^ Enzyme 1.5.3.19 at KEGG Pathway Database.
  2. ^ Chiribau CB, Sandu C, Fraaije M, Schiltz E, Brandsch R (December 2004). "A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1" (PDF). European Journal of Biochemistry. 271 (23–24): 4677–84. doi:10.1111/j.1432-1033.2004.04432.x. PMID 15606755.