4-(dimethylamino)phenylazoxybenzene reductase

4-(dimethylamino)
phenylazoxybenzene
reductase
Identifiers
EC no.1.7.1.11
CAS no.103843-39-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11) is an enzyme that catalyzes the chemical reaction

4-(dimethylamino)phenylazoxybenzene
 
 
H+
H2O
H+
H2O
 
4-(dimethylamino)azobenzene
 

The two substrates of this enzyme are 4-(dimethylamino)phenylazoxybenzene and reduced nicotinamide adenine dinucleotide phosphate (NADPH). Its products are 4-(dimethylamino)azobenzene, oxidised NADP+, and water.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase. Other names in common use include N,N-dimethyl-p-aminoazobenzene oxide reductase, dimethylaminoazobenzene N-oxide reductase, NADPH-dependent DMAB N-oxide reductase, and NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase.

References

  1. ^ Enzyme 1.7.1.11 at KEGG Pathway Database.
  2. ^ Lashmet Johnson PR, Ziegler DM (1986). "Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol". J. Biochem. Toxicol. 1 (1): 15–27. doi:10.1002/jbt.2570010104. PMID 3152268.