2-nitrophenol 2-monooxygenase
| 2-nitrophenol 2-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.31 | ||||||||
| CAS no. | 104520-84-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
2-nitrophenol 2-monooxygenase (EC 1.14.13.31) is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are 2-nitrophenol, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen and a proton. Its products are catechol, oxidised NADP+, water, and nitrous acid.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with molecular oxygen as oxidant and incorporation of one of its atoms into the starting material. The systematic name of this enzyme class is 2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming). Other names in common use include 2-nitrophenol oxygenase, and nitrophenol oxygenase.
References
- ^ Enzyme 1.14.13.31 at KEGG Pathway Database.
- ^ Zeyer J, Kocher HP, Timmis KN (1986). "Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2". Appl. Environ. Microbiol. 52 (2): 334–9. Bibcode:1986ApEnM..52..334Z. doi:10.1128/AEM.52.2.334-339.1986. PMC 203526. PMID 3752997.