2-hydroxybiphenyl 3-monooxygenase
| 2-hydroxybiphenyl 3-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
2-hydroxybiphenyl-3-monooxygenase tetramer, Pseudomonas nitroreducens | |||||||||
| Identifiers | |||||||||
| EC no. | 1.14.13.44 | ||||||||
| CAS no. | 118251-39-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
2-hydroxybiphenyl 3-monooxygenase (EC 1.14.13.44) is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are 2-phenylphenol, reduced nicotinamide adenine dinucleotide (NADH), oxygen, and a proton. Its products are biphenyl-2,3-diol, oxidised NAD+, and water.[1][2]
This enzyme is an oxidoreductase, acting on paired donors, with molecular oxygen as oxidant and incorporation of one of its atoms. The systematic name of this enzyme class is 2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating).
References
- ^ Enzyme 1.14.13.44 at KEGG Pathway Database.
- ^ Kohler HP, Kohler-Staub D, Focht DD (1988). "Degradation of 2-hydroxybiphenyl and 2,2'-dihydroxybiphenyl by Pseudomonas sp. strain HBP1". Appl. Environ. Microbiol. 54 (11): 2683–8. Bibcode:1988ApEnM..54.2683K. doi:10.1128/aem.54.11.2683-2688.1988. PMC 204356. PMID 3214154.